How https://www.ceesdekker.net can Save You Time, Stress, and Money.
How https://www.ceesdekker.net can Save You Time, Stress, and Money.
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Using one-molecule optical and AFM imaging and pressure-spectroscopy tactics, we seek out to unravel the mechanistic aspects of the composition and dynamics of chromosomes. Our exploration passions consist of:
Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular forms with recombination operate.
Dynamics of initiation, termination and reinitiation of DNA translocation with the motor protein EcoR124I
Deposition and atomic power microscopy of individual phthalocyanine polymers involving nanofabricated electrodes
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever design in 2005. (nl)
Within the decades adhering to these discoveries, my research passions shifted to biophysics and nanobiology, And that i grew to become much less linked to the development of nanotube electronics. The main target of many scientists in the field also shifted to graphene (exactly where, funnily enough, the very first graphene ribbons ended up described as ‘nanotubes that happen to be Reduce open up together their length’) immediately after the invention of the two-dimensional product in 2004.
MATLAB codes for info processing are available at . Julia codes useful for numerical simulation can be found at .
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Being familiar with essential procedures regulating the spatial and dynamic organisation of the DNA in live cells.
At this time, we also realized that it ought to be probable to employ a single semiconducting carbon nanotube to create a transistor — and we set out to really make it. We stretched particular person semiconducting nanotubes throughout metallic electrodes and utilised the underlying silicon substrate like a gate electrode, establishing the basic a few-terminal format of a area-effect transistor (Fig.
Illustration (4) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is revealed in gray, the rim in the pore is highlighted in red, and a 3D rendering of your movement on the DNA rod is shown.
2001, discovery of solitary-electron transistors at place temperature based upon nanotubes; realization of first logic circuits with carbon nanotube devices; and discovery from the molecular structure of DNA restore enzymes cees dekker with AFM
Visualization of unstained DNA nanostructures with State-of-the-art in-focus transmission electron microscopy methods
Stable-point out nanopores have tested to generally be a surprisingly versatile probe for single-molecule Evaluation of DNA. I will explain many of our the latest conclusions – precisely DNA knots – and our endeavours to develop the abilities of reliable-condition nanopores even even more, inside the path of single-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.